Immobilization of bioactive molecules within a polymeric substrate
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A method for the immobilization of bioactive molecules within a polymer substrate to be employed as an oral drug delivery system is provided. A water insoluble carrier matrix can be provided that is water swellable, and biologically active agents can be incorporated. The matrix can be a macromolecular network synthesized by gamma radiation at temperatures between −78 degrees Celsius to a boiling point of a component elected for polymerization.
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A61K 9/00, A61K 38/28
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https://worldwide.espacenet.com/patent/search/family/040225125/publication/US2011217378A1?q=pn%3DUS2011217378A1
https://worldwide.espacenet.com/patent/search/family/040225125/publication/US8414923B2?q=pn%3DUS8414923B2
https://patents.google.com/patent/US20110217378A1/en
https://patents.google.com/patent/US8414923B2/en
https://nuclea.cnea.gob.ar/handle/20.500.12553/2809
https://worldwide.espacenet.com/patent/search/family/040225125/publication/US8414923B2?q=pn%3DUS8414923B2
https://patents.google.com/patent/US20110217378A1/en
https://patents.google.com/patent/US8414923B2/en
https://nuclea.cnea.gob.ar/handle/20.500.12553/2809