Determination of inorganic radio-iodides in compounds labelled with 131I by thin layer chromatography II

Abstract

As indicated in a preceding note [1] thin layer chromatography provides a useful tool for recognizing the presence o f radioactive iodide, which is frequently found as the main impurity in 131I-labelled organic compounds used for medical purposes.Radioactive inorganic iodide could be determined quantitatively by thin layer chromatography in the compounds listed in this paper. The chromatograms were developed at room temperature and the activity determination was done with a Radioscanner Packard Model 7200. The spots were also located by autoradiography. In all cases the peaks were well resolved, and 10 cm running o f the solvent was enough to achieve good separation.