Albumin Macroaggregates labelled with Indium-113m for lung scintiscanning

Abstract

A technique is described for the preparation of human serum albumin macroaggreagates, which can be supplied by the CNEA and labelled with Indium-113m by the users, to be applied in lung scintiscanning. Particle sizes range from 10 to 150μ.The labelling technique is simple and insumes 10 min. The final preparation is sterelized by autoclaving. Distribution studies in experimental animals have been made and showed a retention in the lungs of the radioactivity over 95%, 30 min after the intravenous injection.